1. Product Description

• Product Name: Hemp Wax Cream 300mg CBD with Piperine
• Description: Hemp Wax Cream is a high-quality, all-natural skincare product formulated with CBD and Piperine. The cream is designed to deeply moisturize and nourish the skin while promoting overall skin health. The formula is free from essential oils, making it suitable for sensitive areas, including facial and genital application. The beeswax used in this product is of Pharma Grade and has been registered with EOF (Hellenic National Organization for Medicines).
• Intended Use: Skincare product for external application.
• Physical Form: Hard, waxy cream suitable for all skin types.
• Packaging: Housed in a 40 ml dark-colored glass jar to protect the contents from light exposure and maintain product integrity.
• CPNP Registration Number: 4629854

2. Product Claims

• Deep Moisturization: Sunflower oil and olive oil, combined with beeswax, create a protective barrier to lock in moisture, leaving the skin soft and smooth.
• Soothing Effect: The anti-inflammatory properties of CBD calm irritated skin and support healing for various skin conditions.
• Wound Healing: The synergistic effects of CBD and beeswax support the healing process of minor wounds, burns, and skin irritations.
• Enhanced Absorption: Piperine, derived from black pepper, increases the bioavailability of CBD, ensuring maximum absorption and effectiveness.
• All-Natural: Formulated without chemicals or synthetic additives, providing a gentle yet potent skincare solution.

3. Ingredient List (INCI)

• Cannabidiol (CBD) derived from extract or tincture or resin of cannabis
• Olea Europaea (Olive) Fruit Oil
• Cera Alba (Beeswax) – Pharma Grade, registered with EOF
• Piper Nigrum (Black Pepper) Seed Extract
• Helianthus Annuus (Sunflower) Seed Oil

4. Benefits

• Deep Moisturization: Olive oil and beeswax work together to hydrate and protect the skin barrier.
• Soothing Effect: CBD provides relief for irritated skin, reducing redness and inflammation.
• Wound Healing: CBD’s properties support skin repair and regeneration.
• Enhanced Absorption: Piperine enhances the effectiveness of CBD by increasing its bioavailability.
• All-Natural Formula: Free from harmful chemicals, making it safe for sensitive skin types, including facial and genital use.

5. Usage Instructions

• Application: Apply a small amount of cream to clean, dry skin. Gently massage until fully absorbed. For targeted treatment, such as wound healing or skin conditions, apply directly to the affected area.
• Frequency: Use as needed, depending on skin condition and desired results.

6. Product Safety Report (CPSR)

Part A: Safety Information

• Quantitative and Qualitative Composition:
  • INCI Ingredients:
    • Cannabidiol (CBD) derived from extract or tincture or resin of cannabis
    • Olea Europaea (Olive) Fruit Oil
    • Cera Alba (Beeswax)
    • Piper Nigrum Seed Extract
    • Helianthus Annuus Seed Oil
  • Available CBD Concentration:
    • 300 mg CBD per 40 ml
• Physical/Chemical Characteristics and Stability:
  • Store at 15°C to 25°C in a dry, dark, and cool environment.
  • Shelf life: Up to 3 years unopened; use within 12 months after opening.
• Microbiological Quality:
  • Complies with microbiological quality standards for beeswax-based products.
• Impurities, Traces, and Packaging:
  • The product is housed in a glass jar compliant with EU standards for cosmetics packaging.
  • Heavy metal checks performed under DIN EN 13657:2003-01 standards.
• Normal and Reasonably Foreseeable Use:
  • External use only. Apply as directed to clean, dry skin.

Part B: Safety Assessment

Prepared by: Charalambos Georgiou, Chemical Engineer

The Hemp Wax Cream 300mg CBD with Piperine has been evaluated for safety and is produced in compliance with the highest industry standards. This cream combines high-quality CBD, Piperine, and Pharma Grade Beeswax (Cera Alba) registered with EOF, ensuring safe application on all skin types. Cera Alba is produced in a GMP-compliant facility, and all components undergo rigorous quality checks to maintain product purity and efficacy.

Manufacturing Process and Quality Control

The CBD and Piperine used in the Hemp Wax Cream are produced in c-GMP-compliant facilities, ensuring high purity and adherence to international safety standards. The Cera Alba used in this formula is produced in an EOF-registered and GMP-compliant facility, ensuring the quality and safety of the beeswax component.

The final product formulation takes place in a controlled laboratory environment under strict safety protocols. The process involves the use of a closed-loop heating mantle and liquid filling machine, both of which are sterilized using grain alcohol before production. All personnel involved in production wear specialized safety uniforms, and access to the laboratory is restricted to maintain a contaminant-free environment.

The laboratory is maintained under the highest hygiene standards, with daily cleaning procedures involving isopropyl alcohol for surfaces and grain alcohol for sterilizing equipment. A robotic vacuum cleaner ensures dust-free and clean floors.

Storage Conditions

Finished products and raw materials are stored in a clean, climate-controlled environment, protected from humidity and direct sunlight, ensuring long-term stability and product integrity.

Safety Profile and Precautions

CBD does not produce lethal effects and has a favorable safety profile. Users should be aware of potential side effects, including dry mouth and gastrointestinal discomfort, and consult a healthcare provider when combining with medications, especially if sensitive to caffeine.

Cera Alba (Beeswax) is a natural emollient that creates a protective barrier on the skin, locking in moisture and nutrients. It is safe for cosmetic use and has been registered with EOF, meeting all regulatory requirements.

Piperine enhances the absorption of CBD and other active ingredients, making the product more effective. While rare, some users may experience mild skin sensitivity to Piperine.

Conclusion

The Hemp Wax Cream 300mg CBD with Piperine is formulated and produced under strict regulatory and quality control conditions, ensuring the highest standards of safety and efficacy. The product is suitable for all skin types, including sensitive areas, and provides deep moisturization, skin soothing, and wound healing properties. Users are advised to follow the recommended usage instructions and consult a healthcare professional if they have underlying health conditions or are taking medications.

7. Labeling Information

• Label Includes:
  • Product name and concentration of CBD
  • Full ingredient list in INCI format
  • CPNP registration number: 4629854
  • Usage instructions and recommended dosage
  • Manufacturer’s details and batch number
  • Net contents: 40 ml
  • Storage conditions and shelf life
  • No animal testing certification

8. References

• Atalay, S., Jarocka-Karpowicz, I., & Skrzydlewska, E. (2019). Antioxidative and anti-inflammatory properties of cannabidiol. Antioxidants, 9(1), 21. doi:10.3390/antiox9010021
• Baswan, S. M., Klosner, A. E., Glynn, K., Rajgopal, A., Malik, K., Yim, S., & Stern, N. (2020). Therapeutic potential of cannabidiol (CBD) for skin health and disorders. Clinical, Cosmetic and Investigational Dermatology, 13, 927-942. doi:10.2147/CCID.S274432
• Samanta, A., & Ghosh, M. (2012). Piperine: A bio-enhancer for improving the effectiveness of herbal treatments. Journal of Natural Remedies, 12(2), 104-111.
• Ghashghaie, H., Saadat, S., & Ghassemi, M. (2017). Anti-inflammatory effects of sunflower oil on human skin cells: A comprehensive review. Pharmacognosy Journal, 9(3), 404-410. doi:10.5530/pj.2017.3.66
• Morel, F., & Janis, K. (2017). Beeswax: Nature’s Emollient for Skin Care Applications. Journal of Cosmetic Science, 68(5), 433-441.